Table 4.

Coprimary and secondary endpoints

	Intention to treat			Complier average causal effect
	aIRR or aOR*	95% CI	p value	Effect	95% CI
Primary endpoints
Rate of COVID-19-related absence	0·80	0·54–1·19	0·27	0·61	0·30–1·23
Rate of COVID-19-related absence (aggregated dataset)	0·80	0·62–1·03	0·085	0·62	0·29–1·33
Rate of symptomatic PCR-confirmed infection	0·96	0·75–1·22	0·72	0·86	0·55–1·34
Secondary endpoints
Rate of any absence	0·97	0·82–1·16	0·77	0·89	0·71–1·18
Rate of any community testing PCR-confirmed infection	0·96	0·76–1·20	0·71	0·88	0·57–1·41
Proportion of asymptomatic contacts testing PCR-positive on a research PCR test	0·73	0·33–1·61	0·44	..	..
Proportion of contacts testing PCR-positive while symptomatic on a routine community test	1·21	0·82–1·79	0·34	..	..

aIRR=adjusted incidence rate ratio. aOR=adjusted odds ratio.

^*aIRRs are reported for rates, aORs are reported for proportions.