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. 2021 Sep 10;16:6249–6261. doi: 10.2147/IJN.S319348

Table 3.

The Statistics Summary of Complete Factorial Design (32) Used for Optimization of SPs Formulations

Responses R2 Adjusted R2 Predicted R2 Adequate Precision Significant Factors
Y1: EE% 0.93 0.87 0.73 11.39 X1, X2
Y2: VS (nm) 0.92 0.85 0.69 10.12 X1, X2
Y3: PDI 0.94 0.89 0.76 13.23 X1, X2
Y4: ZP (mV) 0.74 0.50 −0.05 4.82 –

Abbreviations: SPs, Spanlastics; EE%, encapsulation efficiency percent; VS, vesicle size; PDI, polydispersity index; ZP, zeta potential.