TABLE 1.
Recipient, donor, and operative factors in patients undergoing split liver transplantation with and without interposition graft
| Arterial reconstruction with interposition graft (n = 46) | Arterial reconstruction without interposition graft (n = 105) | P | ||
|---|---|---|---|---|
| Recipient factors | ||||
| Age at transplant (mean ± S) | 51.5 ± 11.2 | 51.4 ± 10.6 | 0.983 | |
| Sex, male (%) | 27/46 (58.7%) | 68/105 (64.8%) | 0.478 | |
| BMI, median (IQR) | 25.3 (5.2) | 25.0 (5.1) | 0.477 | |
| MELD score, mean ± SD | 17 ± 8 | 19 ± 8 | 0.063 | |
| High MELD score (≥15) | 24/44 (54.5%) | 71/98 (72.4%) | 0.036* | |
| Indication for transplant | Alcohol | 4/46 (8.7%) | 13/105 (12.4%) | 0.183 |
| Hepatitis B or C | 15/46 (32.6%) | 25/105 (23.8%) | ||
| HCC | 14/46 (30.4%) | 17/105 (16.2%) | ||
| PSC | 2/46 (4.3%) | 17/105 (16.2%) | ||
| NASH | 1/46 (2.2%) | 4/105 (3.8%) | ||
| PBC | 0/46 (0%) | 7/105 (6.7%) | ||
| Other | 10/46 (21.7%) | 22/105 (21.0%) | ||
| Retransplant | 2/46 (4.3%) | 1/104 (1.0%) | 0.220 | |
| Donor factors | ||||
| Age, mean ± SD | 30.4 ± 10.2 | 33.0 ± 11.5 | 0.174 | |
| Sex (male, %) | 24/46 (52.2%) | 66/105 (62.9%) | 0.218 | |
| BMI, median (IQR) | 24.7 (4.9) | 23.7 (5.0) | 0.118 | |
| Cause of death | Trauma | 18/46 (39.1%) | 39/105 (37.1%) | 0.913 |
| Cerebrovascular event | 14/46 (30.4%) | 41/105 (39.0%) | ||
| Cardiac arrest | 1/35 (2.2%) | 2/105 (1.9%) | ||
| Respiratory hypoxia | 10/46 (21.7%) | 17/105 (16.2%) | ||
| Other | 3/46 (6.5%) | 5/105 (4.8%) | ||
| Donor risk index, median (IQR) | 1.76 (0.43) | 1.76 (0.38) | 0.736 | |
| Donor recipient weight ratio, median (IQR) | 0.97 (0.30) | 1.07 (0.37) | 0.099 | |
| Operative factors | ||||
| Urgency of transplant | 1—ICU | 3/46 (6.5%) | 5/105 (4.8%) | 0.875 |
| 2—hospital bound | 8/46 (17.4%) | 14/105 (13.3%) | ||
| 3—occasional inpatient | 8/46 (17.4%) | 19/105 (18.1%) | ||
| 4—at home | 27/46 (58.7%) | 67/105 (63.8%) | ||
| Cold ischemia time (min), median (IQR) | 403 (201) | 379 (206) | 0.835 | |
| Warm ischemia time (min), median (IQR) | 47.5 (15) | 45 (19) | 0.292 | |
| Packed cells, mean ± SD | 6 ± 7 | 5 ± 6 | 0.364 | |
| Operative time (min), mean ± SD | 421 ± 217 | 356 ± 107 | 0.015* | |
*P <0.05.
BMI, body mass index; HCC, hepatocellular carcinoma; ICU, intensive care unit; IQR, interquartile range; MELD, model for end-stage liver disease; NASH, nonalcoholic steatohepatitis; PBC, primary biliary cirrhosis; PSC, primary sclerosing cholangitis.