Table 2.
Analysis of GO function enrichment of E2Fs family members and 160 functionally similar genes in ccRCC.
| GO | Category | Description | Count | % | Log10 (P) | Log10 (q) |
|---|---|---|---|---|---|---|
| GO : 0051301 | GO biological processes | Cell division | 32 | 22.22 | −22.64 | −18.29 |
| GO : 0010564 | GO biological processes | Regulation of cell cycle process | 30 | 20.83 | −17.11 | −13.6 |
| GO : 0005819 | GO cellular components | Spindle | 19 | 13.19 | −13.23 | −10.06 |
| GO : 0006260 | GO biological processes | DNA replication | 17 | 11.81 | −13.12 | −10 |
| GO : 0005815 | GO cellular components | Microtubule organizing center | 21 | 14.58 | −9.18 | −6.33 |
| GO : 0007080 | GO biological processes | Mitotic metaphase plate congression | 7 | 4.86 | −8.17 | −5.45 |
| GO : 0071103 | GO biological processes | DNA conformation change | 13 | 9.03 | −7.83 | −5.16 |
| GO : 1990234 | GO cellular components | Transferase complex | 18 | 12.50 | −7.01 | −4.41 |
| GO : 0007062 | GO biological processes | Sister chromatid cohesion | 6 | 4.17 | −6.05 | −3.52 |
| GO : 0031261 | GO cellular components | DNA replication preinitiation complex | 3 | 2.08 | −5.88 | −3.35 |
| GO : 0000076 | GO biological processes | DNA replication checkpoint | 4 | 2.78 | −5.82 | −3.3 |
| GO : 0006513 | GO biological processes | Protein monoubiquitination | 6 | 4.17 | −5.81 | −3.3 |
| GO : 0016363 | GO cellular components | Nuclear matrix | 7 | 4.86 | −5.80 | −3.3 |
| GO : 0030496 | GO cellular components | Midbody | 8 | 5.56 | −5.31 | −2.86 |
| GO : 0043021 | GO molecular functions | Ribonucleoprotein complex binding | 7 | 4.86 | −5.22 | −2.79 |
| GO : 0016607 | GO cellular components | Nuclear speck | 11 | 7.64 | −5.11 | −2.71 |
| GO : 0003682 | GO molecular functions | Chromatin binding | 13 | 9.03 | −4.87 | −2.51 |
| GO : 0016570 | GO biological processes | Histone modification | 11 | 7.64 | −4.47 | −2.2 |
| GO : 0022613 | GO biological processes | Ribonucleoprotein complex biogenesis | 11 | 7.64 | −4.09 | −1.91 |
| GO : 0006368 | GO biological processes | Transcription elongation from RNA polymerase II promoter | 5 | 3.47 | −4.05 | −1.87 |