Table 3.
Correlations between the changes in score of the BDI-II, NMSS mood/apathy domain, and PDQ-39 emotional well‐being domain, and changes in other scales from V1 (baseline) to V4 (6 years ± 15 days)
| BDI-II | NMSS Mood/apathy |
PDQ-39SI Emotional well-being |
|
|---|---|---|---|
| Motor assessment | |||
| UPDRS-III-ON | 0.185 | − 10.004 | 0.215 |
| UPDRS-IV | 0.257 | 0.457** | 0.259 |
| FOGQ | 0.093 | 0.187 | − 10.035 |
| Non motor assessment | |||
| NMSS total score | 0.513* | 0.680 | 0.216 |
| ESS | 0.017 | 0.092 | 0.154 |
| PSQI | 0.022 | 0.352*** | − 10.006 |
| BDI-II | NA | 0.507* | 0.458** |
| KPPS | 0.432** | 0.253 | 0.268 |
| VAS-PAIN | 0.178 | 0.365*** | 0.028 |
| VAFS—Physical | 0.380*** | 0.389*** | 0.07 |
| VAFS—Mental | 0.580* | 0.498** | 0.243 |
| QoL and autonomy | |||
| PDQ-39SI | 0.467** | 0.385*** | 0.522* |
| ADLS | − 10.121 | − 10.289 | − 10.116 |
Spearman correlation test were applied. Significant values are in bold
ADLS Schwab & England Activities of Daily Living Scale, BDI Beck Depression Inventory, ESS Epworth Sleepiness Scale, FOGQ Freezing of Gait Questionnaire, H&Y Hoenh & Yahr, KPPS King’s PD Pain Scale, NMSS Non-Motor Symptoms Scale, NPI Neuropsychiatric Inventory, PDQ-39SI 39-item Parkinson’s Disease Quality of Life Questionnaire Summary Index, PSQI Pittsburgh Sleep Quality Index, UPDRS Unified Parkinson’s Disease Rating Scale, VAFS Visual Analog Fatigue Scale, VAS-Pain Visual Analog Scale-Pain, NA not applicable
*p < 0.0001; **p < 0.001; ***p < 0.05