Table 2.
Effect of WISER intervention (100-point scale) estimated from generalized linear mixed-effects model.
| H1: Efficacy of WISERa | Effect of WISER within the cohort | H4: Full and condensed intervention similarly effectived | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Cohort | H2: 1-monthb | H3: 6-monthc | ||||||||
| Estimate (95% CI) | P-value | Estimate (95% CI) | P-value | Estimate (95% CI) | P-value | Time | Estimate (95% CI) | P-value | ||
| Emotional exhaustion | ||||||||||
| −5.27 (−10.44 −0.10) | 0.046 | C1 | −5.64 (−9.59 −1.68) | 0.005 | −4.85 (−9.25 −0.45) | 0.031 | 1-month | −1.37 (−6.78 4.04) | 0.619 | |
| C2 | −4.27 (−7.96 -0.57) | 0.024 | −1.92 (−5.91 2.07) | 0.346 | 6-month | −2.94 (−8.88 3.00) | 0.332 | |||
| −5.21 (−7.92 −2.51) | <0.001 | C1 + C2 | −3.23 (−6.22 −0.25) | 0.034 | 1.98 (−1.20 5.15) | 0.221 | NA | NA | NA | |
| Depression | ||||||||||
| −1.20 (−5.30 2.89) | 0.564 | C1 | −2.14 (−5.28 1.01) | 0.183 | −6.06 (−9.52 −2.60) | <0.001 | 1-month | 2.72 (−1.55 7.00) | 0.212 | |
| C2 | −4.86 (−7.76 −1.96) | 0.001 | −2.50 (−5.64 0.64) | 0.118 | 6-month | −3.56 (−8.23 1.11) | 0.135 | |||
| −3.72 (−5.75 −1.68) | <0.001 | C1 + C2 | −3.90 (−6.14 −1.67) | <0.001 | −0.19 (−2.55 2.17) | 0.875 | NA | NA | NA | |
| Work-life integration | ||||||||||
| 2.99 (−0.19 6.17) | 0.065 | C1 | 5.18 (2.75 7.60) | <0.001 | 7.33 (4.64 10.01) | <0.001 | 1-month | 1.09 (−2.24 4.43) | 0.520 | |
| C2 | 4.08 (1.80 6.37) | <0.001 | 2.92 (0.47 5.37) | 0.019 | 6-month | 4.40 (0.77 8.04) | 0.018 | |||
| 4.57 (2.97 6.17) | <0.001 | C1 + C2 | 5.07 (3.32 6.82) | <0.001 | 0.50 (−1.36 2.37) | 0.596 | NA | NA | NA | |
| Happiness | ||||||||||
| 1.37 (−1.60 4.34) | 0.366 | C1 | 0.60 (−1.68 2.87) | 0.607 | −0.03 (−2.55 2.48) | 0.979 | 1-month | 1.14 (−1.98 4.25) | 0.474 | |
| C2 | −0.54 (−2.67 1.59) | 0.619 | 0.81 (−1.48 3.09) | 0.489 | 6-month | −0.84 (−4.24 2.56) | 0.628 | |||
| −0.20 (−1.74 1.34) | 0.794 | C1 + C2 | 0.11 (−1.58 1.80) | 0.896 | 0.32 (−1.49 2.13) | 0.731 | NA | NA | NA | |
aHypothesis 1: efficacy of WISER: the intervention will improve NICU healthcare worker burnout (emotional exhaustion; primary outcome), depression, happiness, and work-life integration (secondary outcomes) in cohort 1 compared with waitlist control in cohort 2. (C1: 1-month post-baseline)−(C2: waitlist-baseline).
bHypothesis 2: WISER will be effective at 1 month. C1: 1-month post-baseline; C2: 1-month post-waitlist.
cHypothesis 3: effect of WISER will endure at 6 months. C1: 6-month post-baseline; C2: 6-month post-waitlist.
dHypothesis 4: effect of the condensed cohort 2 intervention will not be less effective than the full intervention in cohort 1. At 1-month: (C1: 1-month post-baseline)−(C2: 1-month post-waitlist); At 6-month: (C1: 6-month post-baseline)−(C2: 6-month post-waitlist).