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. 2021 Sep 10;14:4791–4804. doi: 10.2147/OTT.S317122

Figure 1.

Figure 1

Silencing Met inhibits the proliferation, migration and invasion, while promotes apoptosis in OS cells. (A) The expression of Met after transfection of three different Met siRNAs in 143B and U2OS detected by qRT-PCR. (n=3) *p<0.05, **p<0.01, ***p<0.001. (B) Colony-formation assay of 143B and U2OS after stable transfection of Met Sh Met or N.C. (vector plasmids). (n=3) *p<0.05, **p<0.01. (C) Transwell migration and invasion assay of 143B and U2OS after stable transfection of Met Sh Met or N.C. (vector plasmids). (n=3) **p<0.01, ***p<0.001. (D) Wound-healing assay of 143B and U2OS after stable transfection of Met Sh Met or N.C. (vector plasmids). (n=3) *p<0.05, **p<0.01. (E) The expression of N-cadherin and vimentin in 143B and U2OS detected by Western blot analysis after stable transfection of Met Sh Met or N.C. (vector plasmids). (F) Cell apoptosis rate of 143B and U2OS after stable transfection of Met Sh Met or N.C. (vector plasmids). (n=3) ***p<0.001.