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. 2021 Apr 15;48(11):3595–3605. doi: 10.1007/s00259-021-05350-y

Table 3.

Survival parameters in groups treated with 10 MBq, 20 MBq and 30 MBq of [225Ac]Ac-DOTA-SP

10 MBq (n = 4) 20 MBq (n = 10) 30 MBq (n = 7)
PFS [months] 4.5 2.6 2.3
OS-d [months] 18.0 33.0 nd
OS-t [months] 7.0 5.0 nd
OS-r/c [months] 13.0 12.5 nd

nd, not define

PFS, progression-free survival time

OS-d from the first diagnosis of the tumour to death from any cause

OS-t from the start of treatment was defined as the time from the first cycle of [225Ac]Ac-DOTA-SP treatment to death from any cause

OS-r/c from recurrence or conversion was defined as the time from the diagnosis of recurrence in primary tumours or conversion in secondary, to death from any cause