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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Neurotoxicology. 2021 Jul 2;86:26–36. doi: 10.1016/j.neuro.2021.06.008

Figure 6. GSK3β, CDK5 mRNA levels, and protein levels at PND 20 in the cortex of CD-1 pup mice developmentally exposed to PFOS (kinase pathway).

Figure 6.

Timed-pregnant CD-1 mice were administered with vehicle (0.5% Tween-20 in water) or 1 mg/kg/day PFOS in water with 0.5% Tween-20 via oral gavage from gestation GD1 through PND 20. (A, C) Blots and quantification of GSK3β protein levels normalized to GAPDH. (D) GSK3β mRNA levels. (B, E) Blots and quantification of CDK5 protein levels normalized to GAPDH. (F) CDK5 mRNA levels. Results are expressed as mean ± S.E.M using the two-tailed unpaired t-test n=4 (*P< 0.05, **P< 0.01).