Table 1.

Literature review of the effects of blast exposure on function and structure of ipsilateral and contralateral eyes.

Reference	Species	Blast delivery	Holder	Timepoints	Major findings
Mohan et al., 2013	mouse	custom-built blast chamber 20psi	allowed head movement but more closely resembled our enclosed holder in schematics	1-24h, 7 days, 4-10 months	PERG: decreased amplitude in ipsilateral and contralateral ERG: no change (7 days) OCT: thinner RNFL in ipsilateral but not contralateral
Bricker-Anthony et al., 2014 and 2015	mouse	modified paintball gun 26psi	enclosed holder with very small window	3, 7, 14, 28 days	OMR: larger changes in visual acuity in ipsilateral vs. contralateral (resolved over time) ERG: increased amplitudes at 1 month in ipsilateral only OCT: small retinal detachments in both ipsilateral and contralateral Histology: timing of cell death different in ipsilateral vs contralateral
Reiner et al., 2015	mouse	modified paintball gun 50psi	enclosed with 7.5 mm opening between the eye and ear	2, 4 weeks (histology at 11 weeks)	OMR: decreased visual acuity and contrast sensitivity in ipsilateral and contralateral OCT: ipsilateral - thinning in INL and photoreceptor layers, contralateral - thicker INL
DeMar et al., 2016	rat	compression chamber attached to expansion chamber 20psi	nylon mesh sling attached to metal sled and inserted directly inside expansion chamber	1, 7, 14 days	ERG: severely reduced amplitudes in ipsilateral but not contralateral (in eye-blasted not face-blasted group)
Guley et al., 2019	mouse	modified paintball gun 50-60psi	enclosed with 7.5 mm opening between the eye and ear	3-7 days, 30 days	OMR: decreased contrast sensitivity in ipsilateral and contralateral Histology: Optic nerve loss and GFAP in ipsilateral only, microglial activation at 3 days in ipsilateral and at 30 days in both