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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Adv Drug Deliv Rev. 2021 Jun 16;176:113835. doi: 10.1016/j.addr.2021.113835

Table 1.

Common exosomal markers.

Exosomal marker Gene Functions Reference
Programmed cell death 6-interacting protein ALIX PDCD6IP vesicle trafficking Naseri et al., Int. J. Nanomed., 2018
CD9 antigen CD9 integral membrane protein Naseri et al., Int. J. Nanomed., 2018
Annexin V ANX45 phospholipid-binding Jeppesen et al., Cell, 2019
Heat shock cognate protein 71kDa HSC70 protein folding Kowal et al., PNAS, 2016
CD63 antigen CD63 endosomal cargo sorting Hurwitz et al., Journal of Virology, 2018
CD81 antigen CD81 cell migration Tejera et al., Mol Biol Cell, 2013
Flotillin-1 FLOT1 vesicle trafficking Wang et al., Blood, 2014
Heat shock protein 70kDa HSP70 protein folding Wen et al., Cancer Res., 2016
Tumor susceptibility gene 101 protein TSG101 vesicle trafficking Goh et al., Sci. Rep., 2017
Annexin A2 ANXA2 vesicle trafficking Chaudhary et al., Breast Cancer Res., 2020
Syntenin-1 SDCBP protein trafficking Rontogianni et al., Commun Biol., 2019
Peptidylprolyl isomerase A PPIA intracellular signaling Gomez-Molina et al., Int J Neuropsychophar., 2019
Integrin, beta-1 ITGB1 anchorage to ECM and cell-surface adhesion Clayton et al., FASEB J., 2004