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. Author manuscript; available in PMC: 2022 Sep 14.
Published in final edited form as: Lab Chip. 2021 Sep 14;21(18):3458–3470. doi: 10.1039/d1lc00598g

Fig. 4.

Fig. 4.

(A) Influence of intracellular Ca2+ content on the deformability change of RBCs under cyclic loadings of deoxygenation-oxygenation (DeOxy-Oxy ). Representative fluorescence images of Fluo-4 loaded RBCs under oxygenation and deoxygenation at different time points during the cyclic DeOxy-Oxy loadings. (B) Comparisons of relative intracellular Ca2+ concentration between oxygenated and deoxygenated RBCs at different time points. (C and D) Comparison of changes in the values of μ and η of normal RBCs between of GsMTx-4 incubated samples and DMSO control samples. (E and F) Comparison of changes in the values of μ and η of normal RBCs between of Bafetinib and CHIR-98014 incubated samples and DMSO control samples. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, n.s., not significant.