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. 2021 Mar 4;29(9):1446–1454. doi: 10.1038/s41431-021-00835-8

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© The Author(s) 2021

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Fig. 3 — In each plot, each dot is a genetic variant. The SNP with the most significant P value for PCOS is marked, with the other SNPs colour-coded according to linkage disequilibrium (r²) in Europeans with the lead variant. SNPs with missing linkage disequilibrium information are also coded dark blue. In the left panel, −log10 P values for associations with PCOS risk are on the x-axes, and -log10 P values for associations with the protein levels on the y-axes. On the right panels, genomic positions are on the x-axes, and the y-axes show −log10 P values for PCOS on the upper panel and −log10 P values with the protein levels on the lower panel for the corresponding region. FSH follicle stimulating hormone; PCOS polycystic ovary syndrome; SNP single nucleotide polymorphism.