Table 4.

Results for the three atypical KdVS patients with a KANSL1 variant of unknown significance.

Patient	Variant	Distance to nearest KdVS patient	Median distance of controls to nearest patient	P value
1	c.2542-3C>A	1.3431	1.2971	0.636
2	c.1448G>A (p.(Gly483Glu))	1.1864	1.3012	0.144
3	c.530A>G (p.(Asn177Ser))	1.4651	1.2971	0.877

The results of the analysis for the three patients with a KANSL1 variant of unknown significance. The reference sequences used are: NM_001193466.1 (patient #1), NM_001193466.1 (#2) and NM_015443.3 (#3), respectively.