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. 2021 Sep 1;8:690170. doi: 10.3389/fmolb.2021.690170

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Copyright © 2021 Jiao, Bai, Yin, Liu, Sun, Su, Zeng and Wen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BS inhibited the expressions of fibrosis-related proteins in vivo. (A) The protein levels of α-SMA, Col I, and Col III as measured by Western blot analysis. (B) The protein expressions of TGF-β1, p-Smad2, Smad2, p-Smad3, and Smad3 as measured by Western blot analysis. (C) The protein expressions of TrxR, NF-κB p-p65, and p65 as measured by Western blot analysis. Data were shown as mean ± SD, n ≥ 3 and analyzed with the one-way ANOVA. **p < 0.01 in the model group versus the control group. ^# p < 0.05, ^## p < 0.01, Si, BSL, BSM, and BSH groups versus the model group.