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. 2021 Sep 1;8:706949. doi: 10.3389/fmolb.2021.706949

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Copyright © 2021 Xu, Li, Tang, Liu, Yang and Cheng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression of CD74 was associated with glioma malignancies. (A) Expression of CD74 in glioma and normal brain tissues. The red and grey box represented tumor and normal tissues, respectively. B-E. CD74 expression in different grades (B), IDH status (C), 1p19q status (D), and MGMT status (E) of gliomas. F. Expression of CD74 in different molecular subtypes of glioma. G Immunohistochemistry staining of CD74 in glioma and normal brain tissues. Data were represented as mean ± standard deviation by dot plot. IDH: isocitrate dehydrogenase; MGMT: O6-methylguanine-DNA methyltransferase. *, p < 0.05; ***, p < 0.001; ****, p < 0.0001; ns, no significance.