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. 2021 Sep 1;13:692615. doi: 10.3389/fnagi.2021.692615

TABLE 2.

The morphological and hemodynamic features of IAs in the primary cohort.

Stable IAs n = 341 Rebleeding IAs n = 70 P value
Location, n (%) 0.470
AcomA/ACA 52 (15.2%) 12 (17.1%)
ICA 159 (46.6%) 27 (38.6%)
MCA 117 (34.3%) 26 (37.1%)
PC 13 (3.8%) 5 (7.1%)
Bifurcation, n (%) 142 (41.6%) 42 (60.0%) 0.005+
Irregular shape, n (%) 58 (17.0%) 38 (54.3%) <0.001+
IAsize, mm, M ± SD 5.6 ± 2.9 7.0 ± 2.7 <0.001+
Dome diameter, mm, M ± SD 4.9 ± 3.5 5.0 ± 3.1 0.248
Height, mm, M ± SD 4.5 ± 2.4 4.7 ± 1.9 0.057
AA,°, M ± SD 88.8 ± 19.0 91.3 ± 23.2 0.859
Volume, mm3, m (IQR) 38.4 (19.7–69.4) 40.1 (22.3–90.5) 0.958
Surface area, mm2, m (IQR) 54.8 (33.2–132.1) 50.2 (33.4–180.9) 0.949
AR, M ± SD 1.2 ± 0.4 2.1 ± 0.8 <0.001+
SR, M ± SD 2.1 ± 1.4 3.1 ± 2.2 <0.001+
UI, M ± SD 0.3 ± 0.2 0.4 ± 0.3 0.541
NSI, M ± SD 0.3 ± 0.2 0.3 ± 0.2 0.732
Bottleneck factor, M ± SD 1.2 ± 0.4 1.5 ± 0.5 <0.001+
Height-to-width ratio, M ± SD 1.5 ± 0.5 2.0 ± 0.9 <0.001+
WSSA, Pa, m (IQR) 2.2 (1.2–3.7) 2.7 (1.3–4.1) 0.093
NWSSA, m (IQR) 0.42 (0.26–0.63) 0.22 (0.18–0.28) <0.001+
WSSM, Pa, m (IQR) 6.4 (4.0–9.9) 6.7 (3.3–9.8) 0.580
NWSSM, m (IQR) 1.4 (0.68–2.8) 1.0 (0.57–2.6) 0.227
PA, kPa, m (IQR) 2.3 (1.6–2.8) 2.1 (1.3–2.5) 0.173
NPA, m (IQR) 0.62 (0.44–0.80) 0.57 (0.44–0.77) 0.184
WSSG, m (IQR) 23.0 (16.5–29.1) 16.5 (14.2–25.8) 0.008+
LSAR, m (IQR) 0.28 (0.15–0.45) 0.38 (0.23–0.54) 0.010+
OSI, x10–2, m (IQR) 0.58 (0.20–0.97) 0.70 (0.43–1.73) <0.001+
RRT, m (IQR) 5.79 (3.74–8.22) 4.57 (3.02–7.80) 0.059

+The parameter with significant.

IAs, intracranial aneurysms; MCA, middle cerebral artery; ICA, internal carotid artery; AcomA, anterior communicating artery; ACA, anterior cerebral artery; PC, posterior circulation; AA, aneurysm inclination angle; AR, aspect ratio; SR, size ratio; UI, undulation index; NSI, non-sphericity index; WSSA, wall shear stress average; NWSSA, normalized wall shear stress average; WSSM, wall shear stress maximum; NWSSM, normalized wall shear stress maximum; PA, pressure average; NPA, normalized pressure average; WSSG, wall shear stress gradient; LSAR, low shear area ratio; OSI, oscillatory shear index; RRT, relative resident time.