TABLE 5.
The information of patients and IAs in the validation cohort.
| Characteristics | Stable IAs n = 111 | Rebleeding IAs n = 16 | P value |
| Age, years, M ± SD | 54.6 ± 10.5 | 53.4 ± 5.8 | 0.588 |
| Male, n (%) | 43 (38.7%) | 8 (50.0%) | 0.392 |
| Comorbidities, n (%) | |||
| Hypertension | 40 (36.0%) | 10 (62.5%) | 0.044+ |
| Dyslipidemia | 9 (8.1%) | 3 (18.8%) | 0.175 |
| Diabetes mellitus | 5 (4.5%) | 1 (6.3%) | 0.759 |
| Coronary heart disease | 2 (1.8%) | 0 (0.0%) | 0.590 |
| Ischemic stroke | 3 (2.7%) | 1 (6.3%) | 0.449 |
| History of aSAH | 16 (14.4%) | 2 (12.5%) | 0.837 |
| Modified Fisher scale at admission, n (%) | 0.742 | ||
| I–II | 37 (33.3%) | 6 (37.5%) | |
| III–IV | 74 (66.7%) | 10 (62.5%) | |
| Hunt-Hess grade at admission, n (%) | 0.106 | ||
| I–II | 67 (60.4%) | 13 (81.2%) | |
| III–V | 44 (39.6%) | 3 (18.8%) | |
| Blood pressure | |||
| At admission, n (%) | 0.117 | ||
| <160/90 mmHg | 35 (31.5%) | 2 (12.5%) | |
| >160/90 mmHg | 76 (68.5%) | 14 (87.5%) | |
| Before rebleeding/surgery, n (%) | 0.574 | ||
| <140/80 mmHg | 99 (89.2%) | 15 (93.8%) | |
| >140/80 mmHg | 12 (9.8%) | 1 (6.2%) | |
| Location, n (%) | 0.244 | ||
| AcomA/ACA | 16 (14.4%) | 5 (31.3%) | |
| ICA | 53 (47.7%) | 6 (37.5%) | |
| MCA | 40 (36.1%) | 5 (31.3%) | |
| PC | 2 (1.8%) | 0 (0.0%) | |
| Bifurcation, n (%) | 42 (37.8%) | 13 (81.3%) | 0.001+ |
| Irregular shape, n (%) | 17 (15.3%) | 9 (56.3%) | <0.001+ |
| IAsize, mm, M ± SD | 4.7 (3.8–7.1) | 6.4 (4.5–7.5) | 0.130 |
| Dome diameter, mm, M ± SD | 3.9 (2.9–5.6) | 4.3 (3.2–6.0) | 0.472 |
| Height, mm, M ± SD | 3.8 (3.0–5.7) | 3.9 (3.5–5.4) | 0.520 |
| AA,°, M ± SD | 86.8 (79.9–98.3) | 85.6 (81.3–103.3) | 0.757 |
| Volume, mm3, m (IQR) | 41.6 (19.7–121.9) | 40.3 (29.3–75.5) | 0.870 |
| Surface area, mm2, m (IQR) | 60.7 (34.6–144.84) | 52.2 (46.6–161.0) | 0.951 |
| AR, m (IQR) | 1.2 (0.9–1.5) | 1.9 (1.3–2.3) | <0.001+ |
| SR, m (IQR) | 1.6 (1.2–2.6) | 2.3 (1.3–5.0) | 1.116 |
| UI, m (IQR) | 0.26 (0.15–0.42) | 0.19 (0.12–0.49) | 0.525 |
| NSI, m (IQR) | 0.29 (0.06–0.44) | 0.21 (0.07–0.43) | 0.525 |
| Bottleneck factor, m (IQR) | 1.1 (1.0–1.3) | 1.3 (1.1–1.7) | 0.064 |
| HWR, m (IQR) | 1.4 (1.2–1.7) | 1.9 (1.4–2.5) | 0.024+ |
| WSSA, Pa, m (IQR) | 2.3 (1.4–4.0) | 2.2 (1.0–3.8) | 0.773 |
| NWSSA, m (IQR) | 0.42 (0.26–0.61) | 0.22 (0.18–0.27) | 0.001+ |
| WSSM, Pa, m (IQR) | 6.7 (3.9–11.3) | 6.0 (2.9–10.0) | 0.606 |
| NWSSM, m (IQR) | 1.31 (0.68–2.38) | 1.25 (0.65–2.45) | 0.922 |
| PA, Pa, m (IQR) | 2319.3 (1737.6–2910.7) | 1912.9 (1270.8–2217.9) | 0.008+ |
| NPA, m (IQR) | 0.60 (0.42–0.76) | 0.64 (0.44–0.77) | 0.719 |
| WSSG, m (IQR) | 6.9 (5.4–10.7) | 7.9 (6.3–13.0) | 0.1123 |
| LSAR, m (IQR) | 0.27 (0.16–0.44) | 0.41 (0.26–0.55) | 0.072 |
| OSI, x10–2, m (IQR) | 0.60 (0.17–0.91) | 0.84 (0.51–1.64) | 0.009+ |
| RRT, m (IQR) | 5.3 (3.6–7.2) | 4.5 (3.0–5.9) | 0.286 |
+The parameter was significant.
IAs, intracranial aneurysms; MCA, middle cerebral artery; ICA, internal carotid artery; AcomA, anterior communicating artery; ACA, anterior cerebral artery; PC, posterior circulation; AA, aneurysm inclination angle; AR, aspect ratio; SR, size ratio; UI, undulation index; NSI, non-sphericity index; WSSA, wall shear stress average; NWSSA, normalized wall shear stress average; WSSM, wall shear stress maximum; NWSSM, normalized wall shear stress maximum; PA, pressure average; NPA, normalized pressure average; WSSG, wall shear stress gradient; LSAR, low shear area ratio; OSI, oscillatory shear index; RRT, relative resident time.