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. 2021 Sep 1;15:722894. doi: 10.3389/fnins.2021.722894

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Copyright © 2021 Xie, Guan, Wang, Ma, Wang, Fang and Yin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Brain regions showing significant differences of amplitude of low-frequency fluctuation (ALFF) between patient group and healthy control group at baseline. (B) Brain regions showing significant differences of ALFF between the posttreatment and baseline in the patient group. (C) Conjunction analysis maps of ALFF differences [(baseline vs. controls) ∩ (posttreatment vs. baseline)]. The warm color denoted the region where ALFF is higher, and the cool color denotes the region where ALFF is lower. The color circle denoted the overlapped region of ALFF differences.