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. 2021 Sep 15;22:245. doi: 10.1186/s12931-021-01833-6

Table 2.

Demographic information, disease history and vital signs in the baseline in three different groups in the ITT population

Steroid + Azithromycin Azithromycin Lopinavir/Ritonavir Total P-value
Age—mean (SD)* 58.2 (17.2) 57.6 (15.6) 58.4 (16.0) 58.1 (16.3) 0.889
Sex (Male)—no. (%) 57 (49.1) 55 (50.0) 61 (55.5) 173 (51.5) 0.307
BMI—mean (SD) 28.8 (4.7) 29.4 (5.6) 27.7 (5.8) 28.6 (5.4) 0.068
Smoking—no. (%)
 Never-smoker 38 (82.6) 36 (70.6) 32 (72.7) 106 (75.2) 0.625
 Current smoker 2 (4.4) 6 (11.8) 5 (11.4) 13 (9.2)
 Ex-smoker 6 (13.0) 9 (17.7) 7 (15.9) 22 (15.6)
 Total 46 (100.0) 51 (100.0) 44 (100.0) 141 (100.0)
Comorbidities—no. (%)
 Hypertension 23 (19.8) 30 (27.3) 30 (27.3) 83 (24.7) 0.638
 Diabetes 13 (11.2) 14 (12.7) 14 (12.7) 41 (12.2) 0.964
 Chronic heart disease 7 (6.0) 15 (13.6) 8 (7.3) 30 (8.9) 0.122
 Chronic lung disease, not asthma 4 (3.5) 6 (5.5) 5 (4.6) 15 (4.5) 0.824
 Chronic Kidny Disease 1 (0.9) 1 (0.9) 2 (1.8) 4 (1.2) 0.794
 Mild liver disease 2 (1.7) 1 (0.9) 1 (0.9) 4 (1.2) 0.125
 Rheumatologic disease 0 (0.0) 1 (0.9) 0 (0.0) 1 (0.3) 0.367
 Chronic neurologic disease 5 (4.3) 2 (1.8) 4 (3.6) 11 (3.3) 0.502
Vital signs on admission—no. (%)
 Fever °C—mean (SD) 37.15 (0.69) 37.20 ((0.71) 37.17 (0.69) 37.18 (0.70) 0.884
 Heart rate—mean (SD) 87.45 (14.96) 89.61 (15.23) 87.33 (14.48) 88.11 (14.87) 0.491
 Respiratory rate—median (IQR) 18 (18–20) 19 (18–22) 19 (18–22) 18 (18–21) 0.704
 O2 Saturation %—median (IQR) 90 (88–92) 90 (87–92) 90 (87–92) 90 (88–92) 0.617
 Systolic BP mmHg—mean (SD) 121.84 (16.8) 124.14 (15.4) 123.78 (15.9) 122.91 (16.0) 0.594
 Diastolic BP mmHg—mean (SD) 76.6 (10.1) 77.97 (9.9) 76.32 (9.7) 76.95 (9.9) 0.411