Table 4.
Laboratory evaluation at the baseline in the Modified ITT population
| Steroid + Azithromycin | Azithromycin | Lopinavir/Ritonavir | Total | P-value | |||||
|---|---|---|---|---|---|---|---|---|---|
| N | Mean (SD) | N | Mean (SD) | N | Mean (SD) | N | Mean (SD) | ||
| Blood cell count | |||||||||
| WBC | 87 | 6.74 (3.28) | 91 | 6.53 (2.76) | 93 | 6.69 (3.35) | 271 | 6.65 (3.13) | 0.253 |
| Lymphocyte | 84 | 1.36 (0.86) | 89 | 1.32 (0.89) | 89 | 1.61 (2.15) | 262 | 1.43 (1.44) | 0.919 |
| Neutrophyl | 73 | 4.66 (2.67) | 80 | 4.76 (2.47) | 83 | 5.46 (8.16) | 236 | 4.98 (5.25) | 0.117 |
| Eosinophyl | 35 | 0.16 (0.13) | 43 | 0.21 (0.56) | 47 | 0.22 (0.58) | 125 | 0.2 (0.49) | 0.580 |
| Basophyl | 3 | 0.31 (0.28) | 4 | 0.02 (0.01) | 3 | 0.14 (0.21) | 10 | 0.14 (0.21) | 0.368 |
| Platelet | 77 | 204.25 (72.36) | 87 | 190.4 (75.86) | 82 | 198.88 (72.76) | 246 | 197.56 (73.67) | 0.658 |
| Hb | 84 | 13.32 (2.27) | 89 | 13.56 (2.2) | 93 | 13.64 (1.72) | 266 | 13.51 (2.07) | 0.282 |
| HCT | 82 | 40.36 (5.26) | 87 | 40.57 (5.59) | 88 | 40.35 (4.97) | 257 | 40.43 (5.26) | 0.635 |
| Liver function | |||||||||
| ALT | 70 | 43.36 (27.24) | 75 | 51.94 (43.97) | 67 | 54.78 (57.48) | 212 | 50 (44.47) | 0.398 |
| AST | 70 | 41.07 (33.75) | 75 | 44.35 (31.64) | 67 | 45.22 (36.17) | 212 | 43.54 (33.7) | 0.603 |
| ALKPH | 63 | 191 (71.31) | 66 | 208.3 (93.59) | 57 | 184.19 (64.78) | 186 | 195.05 (78.46) | 0.067 |
| BILI (Dir) | 33 | 0.29 (0.15) | 38 | 0.39 (0.63) | 27 | 0.26 (0.12) | 98 | 0.32 (0.41) | 0.108 |
| BIL (Total) | 33 | 0.8 (0.49) | 40 | 45.04 (262.34) | 27 | 0.68 (0.32) | 100 | 18.47 (166.1) | 0.319 |
| Other laboratory parameters | |||||||||
| CRP | 62 | 27.78 (49.67) | 66 | 37.16 (73.32) | 68 | 31.11 (62.07) | 196 | 32.09 (62.47) | 0.649 |
| ESR | 51 | 47.78 (26.34) | 63 | 37.98 (26.33) | 57 | 40.35 (23.41) | 171 | 41.7 (25.58) | 0.816 |
| FERRITINE | 37 | 530.78 (728.58) | 46 | 720.67 (603.16) | 43 | 426.12 (380.65) | 126 | 564.39 (590.28) | 0.050 |
| LDH | 74 | 641.51 (394.26) | 69 | 628.81 (237.53) | 70 | 651.93 (407.81) | 213 | 640.82 (354.74) | 0.768 |
| PT | 63 | 13.41 (2.66) | 70 | 13.99 (2.85) | 66 | 13.31 (2.26) | 199 | 13.58 (2.61) | 0.278 |
| PTT | 63 | 34.84 (8.56) | 68 | 32.72 (5.75) | 66 | 35.89 (11.38) | 197 | 34.46 (8.9) | 0.941 |
| INR | 61 | 1.13 (0.23) | 68 | 1.12 (0.15) | 61 | 1.07 (0.14) | 190 | 1.11 (0.18) | 0.233 |
| BUN | 81 | 17.2 (10.44) | 89 | 16.88 (8.96) | 80 | 16.74 (8.9) | 250 | 16.94 (9.41) | 0.328 |
| CR | 82 | 1.08 (0.73) | 91 | 1.01 (0.29) | 84 | 2.18 (10.92) | 257 | 1.41 (6.25) | 0.471 |
| Uric acid | 21 | 6.77 (6.52) | 24 | 6.03 (4.24) | 21 | 33.15 (109.88) | 66 | 14.9 (62.39) | 0.344 |
| BS | 69 | 130.33 (52.07) | 64 | 130.63 (51.33) | 63 | 128.65 (63.84) | 196 | 129.89 (55.61) | 0.351 |
| HBA1C | 12 | 6.93 (1.84) | 13 | 7.75 (1.97) | 15 | 6.95 (1.84) | 40 | 7.2 (1.87) | 0.868 |
| Na | 80 | 137.99 (4.57) | 81 | 138.21 (4.28) | 84 | 138.12 (4.91) | 245 | 138.11 (4.58) | 0.990 |
| K | 79 | 4.03 (0.47) | 84 | 10.63 (47.23) | 84 | 3.99 (0.53) | 247 | 6.26 (27.61) | 0.177 |
| Ca | 35 | 8.81 (0.73) | 39 | 8.91 (0.79) | 43 | 8.74 (0.64) | 117 | 8.82 (0.72) | 0.677 |
| Mg | 33 | 2.02 (0.27) | 36 | 5.28 (19.16) | 38 | 2.38 (1.99) | 107 | 3.24 (11.17) | 0.391 |
| Phosphorus | 31 | 3.45 (0.91) | 34 | 3.44 (0.64) | 36 | 3.44 (0.6) | 101 | 3.44 (0.72) | 0.879 |
| Vitamine D | 12 | 60.08 (63.62) | 15 | 127.27 (191.15) | 14 | 90.64 (97.16) | 41 | 95.1 (133.16) | 0.370 |
| TROPONINE | 44 | 27.23 (153.31) | 48 | 4.84 (29.35) | 55 | 0.24 (1.03) | 147 | 9.82 (85.64) | 0.319 |
| DDIMER | 36 | 202.23 (427.91) | 34 | 133.02 (322.12) | 33 | 122.08 (329.15) | 103 | 153.71 (362.88) | 0.504 |