Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Leaky and compressed tumor blood vessels. Big transendothelial and interendothelial channels, discontinuous or absent basal membrane, and detached pericytes make tumor blood vessels hyperpermeable to circulating molecules. Stromal components such as fibroblasts, collagen and hyaluronan could compress blood vessels and make some vessels partially open or totally collapsed
