Table 1.
Enriched pathways and gene ontologies associated with MAX dimerization protein 3 (MXD3) and functional protein partners.
| Index | KEGG pathways | p value | Adjusted p value | Odds ratio | Combined score |
|---|---|---|---|---|---|
| 1 | Rap1 signaling pathway | 0.005462 | 0.05462 | 21.55 | 112.29 |
| 2 | Shigellosis | 0.03518 | 0.09465 | 31.13 | 104.21 |
| 3 | Complement and coagulation cascades | 0.04261 | 0.09465 | 25.53 | 80.55 |
| 4 | Salmonella infection | 0.04631 | 0.09465 | 23.42 | 71.95 |
| 5 | Morphine addiction | 0.04894 | 0.09465 | 22.11 | 66.71 |
| 6 | Parathyroid hormone synthesis, secretion, and action | 0.05679 | 0.09465 | 18.94 | 54.32 |
| 7 | Protein processing in endoplasmic reticulum | 0.08712 | 0.1240 | 12.09 | 29.50 |
| 8 | Chemokine signaling pathway | 0.09970 | 0.1240 | 10.48 | 24.15 |
| 9 | Regulation of actin cytoskeleton | 0.1116 | 0.1240 | 9.28 | 20.36 |
| 10 | Endocytosis | 0.1263 | 0.1263 | 8.13 | 16.81 |
| Index | Biological processes | p value | Adjusted p value | Odds ratio | Combined score |
| 1 | Response to lead ions (GO:0010288) | 0.003296 | 0.03288 | 399.68 | 2284.21 |
| 2 | Negative regulation of membrane potential (GO:0045837) | 0.003296 | 0.03288 | 399.68 | 2284.21 |
| 3 | Positive regulation of phospholipid transport (GO:2001140) | 0.003296 | 0.03288 | 399.68 | 2284.21 |
| 4 | Response to misfolded proteins (GO:0051788) | 0.003844 | 0.03288 | 333.05 | 1852.16 |
| 5 | Cellular phosphate ion homeostasis (GO:0030643) | 0.003844 | 0.03288 | 333.05 | 1852.16 |
| 6 | Cellular divalent inorganic anion homeostasis (GO:0072501) | 0.003844 | 0.03288 | 333.05 | 1852.16 |
| 7 | Positive regulation of lymphocyte apoptotic process (GO:0070230) | 0.003844 | 0.03288 | 333.05 | 1852.16 |
| 8 | Cellular trivalent inorganic anion homeostasis (GO:0072502) | 0.003844 | 0.03288 | 333.05 | 1852.16 |
| 9 | Positive regulation of lipid transport (GO:0032370) | 0.003844 | 0.03288 | 333.05 | 1852.16 |
| 10 | Cellular monovalent inorganic anion homeostasis (GO:0030320) | 0.004392 | 0.03288 | 285.46 | 1549.44 |