Table 3. Association between periconceptional passive smoking and risk for fetal NTDs subtypes in five counties, Shanxi Province, China, 2010–2016.
Groups | Number | Number of passive smoking exposure | Crude OR (95% CI) | Adjusted OR* (95% CI) |
*Adjusted for maternal age, prepregnancy BMI, education, fever or flu in early pregnancy, nausea and vomiting during pregnancy (NVP), periconception folic acid use and history of birth defect-affected pregnancy.
Abbreviations: NTDs=neural tube defects; OR=odds ratio; CI=confidence interval; BMI=body mass index. | ||||
Control | 523 | 154 | 1.0 | 1.0 |
Anencephaly | 78 | 42 | 2.795 (1.724−4.532) | 2.497 (1.433−4.352) |
Spina bifida | 121 | 78 | 4.346 (2.864−6.596) | 3.907 (2.404−6.348) |
Encephaloceles | 25 | 13 | 2.596 (1.158−5.817) | 2.540 (1.043−6.188) |