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. 2021 Sep 15;14:145. doi: 10.1186/s13045-021-01159-2

Table 4.

Intensified conditioning regimens

Conditioning regimen Drugs Dose(total) Schedule(day)
International regimens
Cy/VP/TBI Cy 120 mg/kg  − 6, − 5
Vp16 30–60 mg/m2  − 4
FTBI 12.0–13.8 Gy  − 3 to  − 1
TBI/TT/Cy FTBI 13. 8 Gy  − 9 to  − 6
TT 10 mg/kg (po)  − 5, − 4
Cy 120 mg/kg  − 6, − 5
Bu/Cy/MEL Bu 16 mg/kg (po)  − 7 to  − 4
Cy 120 mg/kg  − 3, − 2
Mel 140 mg/m2  − 1
Chinese regimens
TBI/VP16 Flu 150 mg/m2 − 10 to − 6
Ara-C 5–10 g/m2 − 10 to − 6
TBI 9 Gy − 5, − 4
Cy 120 mg/kg − 3, − 2
Vp16 30 mg/kg − 3, − 2
Bu/Cy/IDA IDA 45 mg/m2 − 11 to − 9
Bu 9.6 mg/kg(iv) − 6 to − 4
Cy 3.6 g/m2 − 3, − 2
Bu/Flu/IDA Flu 150 mg/m2 − 21 to − 17
Ara-C 5 g/m2 − 21 to − 17
IDA 30–36 mg/m2 − 17 to − 15
Flu 150 mg/m2/day − 7 to − 3
Bu 9.6 mg/kg(iv) − 5 to − 3
Dec/Bu/Cy/Flu Decitabine 100 mg/m2 − 9 to − 5
Ara-C 6 g/m2 − 9 to − 7
Bu 9.6 mg/kg(iv) − 9 to − 7
Flu 90 mg/m2 − 6 to − 4
Cy 80 mg/kg − 3, − 2

Bu, busulfan; Cy, cyclophosphamide; CsA,cyclosporine; IDA, Idarubicin; Flu, fludarabine, IV, intravenous; VP16, etoposide TBI, Total body irradiation