Table 4.
Conditioning regimen | Drugs | Dose(total) | Schedule(day) |
---|---|---|---|
International regimens | |||
Cy/VP/TBI | Cy | 120 mg/kg | − 6, − 5 |
Vp16 | 30–60 mg/m2 | − 4 | |
FTBI | 12.0–13.8 Gy | − 3 to − 1 | |
TBI/TT/Cy | FTBI | 13. 8 Gy | − 9 to − 6 |
TT | 10 mg/kg (po) | − 5, − 4 | |
Cy | 120 mg/kg | − 6, − 5 | |
Bu/Cy/MEL | Bu | 16 mg/kg (po) | − 7 to − 4 |
Cy | 120 mg/kg | − 3, − 2 | |
Mel | 140 mg/m2 | − 1 | |
Chinese regimens | |||
TBI/VP16 | Flu | 150 mg/m2 | − 10 to − 6 |
Ara-C | 5–10 g/m2 | − 10 to − 6 | |
TBI | 9 Gy | − 5, − 4 | |
Cy | 120 mg/kg | − 3, − 2 | |
Vp16 | 30 mg/kg | − 3, − 2 | |
Bu/Cy/IDA | IDA | 45 mg/m2 | − 11 to − 9 |
Bu | 9.6 mg/kg(iv) | − 6 to − 4 | |
Cy | 3.6 g/m2 | − 3, − 2 | |
Bu/Flu/IDA | Flu | 150 mg/m2 | − 21 to − 17 |
Ara-C | 5 g/m2 | − 21 to − 17 | |
IDA | 30–36 mg/m2 | − 17 to − 15 | |
Flu | 150 mg/m2/day | − 7 to − 3 | |
Bu | 9.6 mg/kg(iv) | − 5 to − 3 | |
Dec/Bu/Cy/Flu | Decitabine | 100 mg/m2 | − 9 to − 5 |
Ara-C | 6 g/m2 | − 9 to − 7 | |
Bu | 9.6 mg/kg(iv) | − 9 to − 7 | |
Flu | 90 mg/m2 | − 6 to − 4 | |
Cy | 80 mg/kg | − 3, − 2 |
Bu, busulfan; Cy, cyclophosphamide; CsA,cyclosporine; IDA, Idarubicin; Flu, fludarabine, IV, intravenous; VP16, etoposide TBI, Total body irradiation