TABLE 3.

Subgroup analysis of BMD alteration in subjects of different age

	Spine		Total hip		Femoral neck		Forearm		Trochanter
	STD (95% CI)	P	STD (95% CI)	P	STD (95% CI)	P	STD(95% CI)	P	STD (95% CI)	P
Mean Age
Old age	0.09(0.02,0.16)	0.02	0.23(−0.14,0.60)	0.23	‐	‐	0.00(−0.06,0.06)	0.93	‐	‐
Adults	0.66(0.51, 0.81)	0.0009	0.44(0.08,0.80)	0.02	0.76(0.15,1.38)	0.02	−1.10(−3.48,1.28)	0.37	0.49(−0.02,1.01)	0.06
Adolescence	0.27(−0.02,0.55)	0.06	‐	‐			0.07(−0.42, 0.55)	0.78
Gender
Women	0.05 (0.00, 0.09)	0.05	0.04 (0.01, 0.07)	0.01	0.06 (0.02, 0.10)	0.002	−0.01 (−0.06, 0.03)	0.60	0.49(−0.02,1.01)	0.06
Men	0.07 (−0.02, 0.15)	0.12	0.02 (−0.03, 0.06)	0.45	‐	‐	−0.00 (−0.02, 0.01)	0.41	‐	‐
Recruitment
Population based	0.26(0.08,0.45)	0.006	0.35 (0.05, 0.66)	0.02	‐	‐	0.02 (−0.03, 0.07)	0.50	‐	‐
Clinical samples	0.59(0.27,0.90)	0.0003	0.70 (0.10, 1.29)	0.02	0.76 (0.15, 1.38)	0.02	−1.11 (−3.48, 1.25)	0.36	0.49(−0.02,1.01)	0.06
Diagnostic criteria
Self‐rating	0.26(0.08,0.45)	0.006	0.35 (0.05, 0.66)	0.02	‐	‐	0.02 (−0.03, 0.07)	0.50	‐	‐
Diagnostic interviews	0.59(0.27,0.90)	0.0003	0.70 (0.10, 1.29)	0.02	0.76 (0.15, 1.38)	0.02	−1.11 (−3.48, 1.25)	0.36	0.49(−0.02,1.01)	0.06
Measuring methods
CT	0.23 (−0.07, 0.53)	0.14	‐	‐	‐		‐	‐	‐	‐
DEXA	0.52 (0.31, 0.73)	<0.00001	0.49 (0.24, 0.75)	0.0001	0.93 (0.32, 1.55)	0.003	−0.12 (−0.34, 0.10)	0.29	0.49(−0.02,1.01)	0.06