Skip to main content
The EMBO Journal logoLink to The EMBO Journal
. 2021 Sep 15;40(18):e109151. doi: 10.15252/embj.2021109151

Caspase‐12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein

Claudio Hetz , Milene Russelakis‐Carneiro, Kinsey Maundrell, Joaquin Castilla, Claudio Soto
PMCID: PMC8441498  PMID: 34523135

Abstract

graphic file with name EMBJ-40-e109151-g001.jpg


Correction toThe EMBO Journal (2003) 22: 5435–5445. DOI 10.1093/emboj/cdg537 ¦ Published online 15 October 2003

graphic file with name EMBJ-40-e109151-g003.jpg

Figure 7A. Original.

Source data are available online for this figure.

graphic file with name EMBJ-40-e109151-g002.jpg

Figure 7A. Corrected.

Source data are available online for this figure.

The journal was informed of potential image aberrations in Fig 7A. The authors claim that the loading control in the originally published figure corresponded to a replicate experiment as many Western blots were run in parallel with the same samples to measure levels of ER stress markers. The control panel in Fig 7A is herewith retracted and replaced with the author‐supplied loading control of the experiment shown in Fig 7A.

The journal noted that Fig 3 and Appendix Figure 3 were duplicated and that the legend to Appendix Figure 3 did not match the displayed figure. The authors recovered the quantification data for Appendix Figure 3, but not the scanned blots. The authors state that they no longer have access to the laboratory books or primary data and that they cannot definitively say which image was analysed. The authors withdraw Appendix Figure 3.

The authors also acknowledge that there are undeclared splice sites in Fig 3, but that they could not locate the source data.

The source data for Fig 7A are available with this corrigendum notice.

The authors apologize for these errors and agree with this corrigendum; no response could be obtained from MR‐C.

Supporting information

Source Data for Figure 7A

EMBJ-40-e109151-s001.pdf (453.8KB, pdf)

The EMBO Journal (2021) 40: e109151.

Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Supplementary Materials

Source Data for Figure 7A

EMBJ-40-e109151-s001.pdf (453.8KB, pdf)

Articles from The EMBO Journal are provided here courtesy of Nature Publishing Group

RESOURCES