TABLE 2.

The biological activity of bioactive peptides from different strains

Activity	Bioactive peptides	References
Antioxidant activity	Tetrapeptide MGRY (MW = 526) from Pavlova lutheri showed the ability to scavenge for free radicals	Oh et al. (2015)
Antiproliferative activity	Peptide obtained from Chlorella inhibited UVB‐induced c‐fos and c‐jun expressions	Chen et al. (2011)
	Peptide derived from chlorella inhibited cytotoxicity caused by UVC, reduce pFADD expression, decrease cleaved PARP‐1, and prevent DNA damage and fragmentation	Fen and Yuh (2012)
Anti‐inflammatory activity	Spirulina‐derived peptides increased hydration and reduce osmotic stress in skin cells	Chiu‐Lan et al. (2011)
Antimicrobial activity	Protein fraction of Chlorella vulgaris with 62 kDa had antimicrobial activity against E. coli CECT 434	Sedighi et al. (2019)
	AQ‐1766 peptide (LWFYTMWH) from Tetraselmis suecica had antimicrobial activity against the Gram‐negative and Gram‐positive bacterial strains	Guzmán et al. (2019)
Antitumoral activity	Suppress PMA‐induced secretion of matrix metalloproteinase‐9 through the inactivation of the JNK, p38, and NF‐κB pathways in human fibrosarcoma cells	Heo et al. (2018)
Antihypertensive activity	Peptide fractions isolated from Spirulinas inhibited angiotensin I converting enzyme	Heo et al. (2017)
	Peptides from Vischeria helvetica KGU‐Y001 had molecular weights lower than 400 Da and high ACE inhibitory activities	Aburai et al. (2020)
	Peptides from Chlorella sorokiniana showed ACE inhibitory activity	Lin et al. (2018)