FIGURE 2.
Neutralization of the SARS‐CoV‐2 pseudovirus and live virus and the SARS‐CoV‐2(V367F) pseudovirus by mAbs. (A and B) SARS‐CoV‐2 and SARS‐CoV‐2(V367F) pseudovirus were incubated with threefold serially diluted mAbs. The mixtures were then added to Huh7 cells. After 24 h incubation, neutralization potencies of mAbs were evaluated in a luciferase assay system. (C) The mixture of live SARS‐CoV‐2 virus and serially diluted mAbs was added to Vero‐E6 cells. After 72 h incubation, ND50 was calculated by fitting the CPE proportion with serially diluted antibody to a sigmoidal dose‐response curve. (D) CPE for representative MA9 was observed daily and recorded on day 3 post‐exposure