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. 2021 Jul 29;77(1):271–281. doi: 10.1111/all.15007

TABLE 1.

Demographic characteristics with N‐Protein IgG and S‐Protein levels (First jab)

Repeated negative RT‐PCR in the last 12 months (n = 735) Positive RT‐PCR (n = 270) p value

Negative N‐Protein IgG a

(n = 693)

Positive N‐Protein IgG b

(n = 42)

9 to 12 months ago c

(n = 94)

3 to 7 months ago d

(n = 176)

Sex
Female (%) 484 (69.8) 35 (83.3) 66 (70.2) 139 (78.0) 0.03
Male (%) 209 (30.2) 7 (16.7) 28 (29.8) 37 (21.0)
Age, mean (SD), range, year

86.2 (0.0)

51–106

85.3 (7.0)

72–100

86.6 (9.2)

54–100

87.8 (8.2)

54–100

0.05
SARS‐CoV−2 N‐Protein IgG level ≥0.8 signal to cutoff ratio, No. (%) 0 42 (100) 55 (61.1) 144 (83.7) <0.001 between c and d
SARS‐CoV−2 N‐Protein IgG level, median (IQR) [range], AU/ml 0

3.4 (0.8;7.3),

[0.8–7.3]

1.0 (0.4;2.6)

[0.02–6.1]

3.91 (1.9;5.3) [0.01–8] <0.001 between c and b , d
SARS‐CoV−2 S‐protein IgG level
0–50 AU/ml 288 (41.7) 5 (11.9) 8 (4.6) 2 (2.1)
50–1050 AU/ml 343 (49.6) 5 (11.9) 15 (8.6) 6 (6.4)
1050–4160 AU/ml 47 (6.8) 1 (2.4) 5 (2.8) 3 (3.2)
≥4160 AU/ml 13 (1.9) 31 (73.8) 147 (84.0) 83 (88.3)
SARS‐CoV−2 S‐protein level median (Q1‐Q3) [range], AU/ml

82 (16–296)

[0–40,000]

21,736 (16,229)

[0–40,000]

40,000 (9,146–40,000) [6–14142] 20,796 (4157;40000) [1–40,000]

<0.001 between a and b , c , d

<.001 between c and b , d

a

Corresponds to residents with negative RT‐PCR in the last 12 months and with negative N‐Protein IgG.

b

Corresponds to residents with negative RT‐PCR in the last 12 months and with positive N‐Protein IgG.

c

Corresponds to residents with posittive RT‐PCR in the last 9‐12 months.

d

Corresponds to residents with positive RT‐PCR in the 3 to 7 months ago.