TABLE 4.
Length changes in FMR1 (CGG)n arrays in sgs1, rad27, exo1, and din7 cells
| Mutation | Array | Orientation | No. of strains | No. (repeats) of expansions (%) | No. (%) of contractions |
|---|---|---|---|---|---|
| sgs1 | 9A48 | (+) | 69 | 0 | 1 (1.4) |
| 9A48 | (−) | 68 | 0 | 4 (5.9) | |
| 74 | (+) | 45 | 0 | 5 (11.1) | |
| 74 | (−) | 48 | 0 | 1 (2.1) | |
| rad27 | 10A9A9 | (+) | 46 | 0 | 9 (19.6) |
| 10A9A9 | (−) | 48 | 3 (+20, +20, +40) (6.25) | 2 (4.2) | |
| 9A48 | (+) | 45 | 2 (+5, +5) (4.4) | 11 (24.4) | |
| 9A48 | (−) | 92 | 16 (+5 to +50)a (17.4) | 18 (19.6) | |
| exo1 | 9A48 | (+) | 48 | 0 | 8 (16.7) |
| 9A48 | (−) | 48 | 0 | 2 (4.2) | |
| din7 | 9A48 | (+) | 48 | 0 | 5 (10.4) |
| 9A48 | (−) | 48 | 0 | 4 (8.3) |
a
In addition, a further 4 of 92 colonies showed evidence of expansion during sibling colony growth.