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. 2021 Jun 30;22(2):e00105-21. doi: 10.1128/jmbe.00105-21

TABLE 1.

Qualitative analysis codebook for the class topic aquaporins along with percentages (n = 77) of student responses in each code

Code Description of code (student writes about/a…) Example student response Percentage of responsesb
Evolution (EVO)
Aquaporins evolved from prokaryote to eukaryote how eukaryotes have aquaporins after evolving from prokaryotes. “Since aquaporins are in bacteria, we can say that is one of the most basic structures in life.” 20% aOther 19%; Blank 0%
All living things have aquaporins the origin of aquaporins from a common ancestor. “Bacteria, animals, plants, they all have them.” 61%
Structure and Function (SF)
Function only what aquaporins do “transmembrane protein that allows for osmosis” 27% Other 21%; Blank 0%
Structure only about the molecular structure of aquaporins “must be hydrophobic and hydrophilic in order to be in and out of phospholipid bilayer” 27%
Both codes [Function only] and [Structure only] “The protein has to have hydrophobic amino acids and hydrophilic amino acids in order for the water to move through the protein” 25%
Information Flow, Exchange and Storage (IFES)
Communication between proteins how proteins (aquaporins) communicate with one another “the communication of certain proteins to open and close the channels” 12% Other 24%; Blank 3%
Transport of water water molecules being transferred and/or the phenomenon of osmosis “osmosis, H2O molecule sharing” 61%
Pathways of Transformation of Energy and Matter (PTEM)
Energy required the use of energy by aquaporins “water is leaving/entering the cell. Requires energy tomove through channel” 5% Other 25%; Blank 0%
No energy required diffusion, as a no energy mechanism facilitated by aquaporins “No, water is just passing through” 18%
Transport of water the matter, being the water molecules transported “water is going through” 41%
Both codes [No energy required] and [Transport of water] “H2O is being transferred no energy is used” 11%
Systems (SYS)
Aquaporin structure the aquaporin structure, being a system “a series of polypeptides that differ…[]” 12% Other 19%; Blank 0%
How the system (osmosis) works the aquaporins functioning as a system “Osmosis or/and diffusion” 29%
List of cell membrane elements list of cell membrane elements “water channel, cell membrane” 40%
a

The code “Other” indicates incomplete or irrelevant responses to the specific CC and topic.

b

Boldface text indicates the highest percentage of student responses in each CC.