Induction of macroscopic foci in RK3E cells following infection with retroviruses encoding mutated forms of β-cat but not wild-type (WT) β-cat. The specific proteins encoded by the retroviruses used for infection, including a control LacZ virus, are indicated in each panel. Schematic representations of the β-cat proteins are shown in Fig. 1A. Four weeks after infection with the retroviruses, the plates were fixed, stained, and photographed, as described in the text.