Figure 3.

Meningeal neural progenitors are widespread in the central nervous system (CNS). Schematic representation of a sagittal section of rodent brain and spinal cord showing the distribution of neural stem cells (NSCs, blue), immature neurons (brown), and oligodendrocyte precursor cells (OPCs, green) in CNS meninges (light blue). The specific markers expressed by each neural progenitor subclass are shown for each area accordingly with the reviewed literature. As meninges cover the entire CNS (brain and spinal cord) and are widely distributed, also meningeal neural progenitors are not restricted to a defined meningeal area of the brain. Specifically, they have been found in the external brain meninges (upper left panel), in the meninges of perivascular space (upper middle panel), in the cerebellar meninges (upper right panel), along the meninges of hippocampal fimbria (lower left panel), in the meningeal substructures (lower middle panel), and in spinal cord meninges (lower right panel).