Table 1.
Demographics, clinical and cognitive characteristics
| CON | SCZ | Statistics | ||
|---|---|---|---|---|
| n=67 | n=84 | t/χ2 | p | |
| Sex [male:female] | 41:26 | 57:27 | 0.73 | 0.394 |
| Race [W:AA:O] | 48:13:6 | 55:27:2 | 5.53 | 0.063 |
| Handedness [R:L] | 60:7 | 77:7 | 0.20 | 0.656 |
| Mean±SD | Mean±SD | |||
| Age [years] | 28.8±9.1 | 27.3±9.4 | 1.04 | 0.302 |
| Maternal education [years] | 14.6±2.4 | 14.6±2.7 | −0.16 | 0.874 |
| Paternal education [years] | 15.1±2.8 | 14.8±3.6 | 0.57 | 0.571 |
| Illness duration [months] | - | 76.9±97.1 | - | - |
| Antipsychotic dosage (Chlorpromazine equivalents) | - | 368.0±220.4 | - | - |
| PANSS Positive | - | 15.8±8.8 | - | - |
| PANSS Negative | - | 14.3±5.4 | - | - |
| PANSS General | - | 28.7±8.1 | - | - |
| WTAR Premorbid IQ | 107.9±15.0 | 102.1±9.5 | 2.93 | 0.004 |
| WMS-III Working Memory Index | 106.7±12.4 | 94.8±11.0 | 6.25 | <0.001 |
| SCIP Verbal Leaning-Immediate z-score | 0.39±0.88 | −0.86±1.26 | 6.88 | <0.001 |
| SCIP Verbal Leaning-Delayed z-score | 0.17±0.97 | −0.83±1.20 | 5.54 | <0.001 |
| SCIP Working Memory z-score | 0.32±0.97 | −0.70±1.32 | 5.32 | <0.001 |
| SCIP Verbal Fluency z-score | 0.64±1.04 | −0.10±1.10 | 4.19 | <0.001 |
| SCIP Processing Speed z-score | −0.20±1.05 | −1.59±1.06 | 7.99 | <0.001 |
| SCIP Global Cognition z-score | 0.26±0.59 | −0.81±0.76 | 9.54 | <0.001 |
| AX-CPT d’-Context | 3.6±0.7 | 2.7±1.0 | 5.92 | <0.001 |
| WCST Total Correct | 52.4±6.5 | 45.7±11.4 | 4.18 | <0.001 |
| tfMRI Total Correct Number | 25.1±3.8 | 22.5±5.6 | 3.20 | 0.002 |
| tfMRI Total Response Time [ms] | 1085.7±381.3 | 1306.0±591.0 | −2.64 | 0.009 |
W-white; AA-African American; O-others; WTAR-Wechsler Test of Adult Reading; PANSS-Positive and Negative Syndrome Scale; WMS-III: Wechsler Memory Scale, third version; SCIP-Screen for Cognitive Impairment in Psychiatry; AX-CPT-AX Continuous Performance Task; WCST-Wisconsin Card Sorting Test.