Table 2.
Comparison of antibiotic prescribing outcomes in intervention and control clinics for main infections combineda
| Arm | N | Crude Rate | Unadjusted GEE Estimate | Adjusted GEE Estimatec | ||
|---|---|---|---|---|---|---|
| OR (95% CIb) | P | OR (95% CI) | p | |||
| Total Antibiotic Prescriptions | ||||||
| Control | 763 | 325 (42.6%) | ||||
| Intervention | 609 | 297 (48.8%) | 1.72 (1, 2.98) | 0.05 | 0.78 (0.64, 0.96) | 0.02 |
| Delayed Antibiotic Prescriptions | ||||||
| Control | 324d | 38 (11.7%) | ||||
| Intervention | 294 | 65 (22.1%) | 1.13 (0.47, 2.68) | 0.79 | 2.29 (1.37, 3.83) | <0.01 |
| Prescription Duration Longer than 7 Dayse | ||||||
| Control | 273 | 80 (29.3%) | ||||
| Intervention | 258 | 55 (21.3%) | 0.34 (0.12, 1.01) | 0.05 | 0.24 (0.13, 0.43) | <0.0001 |
| First Line Antibiotic Choicef | ||||||
| Control | 232 | 197 (84.9%) | ||||
| Intervention | 258 | 238 (92.2%) | 2.2 (2.02, 2.4) | <0.0001 | 1.41 (0.66, 3.01) | 0.37 |
aURI, sore throat, acute sinusitis, acute bronchitis, acute cystitisb 95% confidence interval; cadjusted for case-mix of conditions, age, sex, afterhours visits, and baseline prescribing rate; d denominators differ from total prescriptions in some cases due to missing data; e sore throat cases excluded from analysis fexcluding URI and bronchitis where any antibiotic is considered inappropriate