Table 4.
Significant prognostic factors | EBUS positivity in echelon 3 | |||
---|---|---|---|---|
Univariable analysis | Multivariable analysis | |||
OR (95%-CI) | p-value, χ2-test | OR (95%-CI) | p-value, χ2-test | |
PET-positivity vs. negativity in echelon-3 | 12.7 (3.5–46.4) | 0.0001 | 12.1 (3.2–46.5) | 0.0003 |
EBUS-positivity vs. negativity in echelon-2 | 5.9 (1.3–26.7) | 0.021 | 6.7 (1.31–31.2) | 0.022 |
Laterality (left-sided tumors compared with right-sided) | 2.8 (1.01–7.9) | 0.049 | 4.0 (1.24–13.2) | 0.020 |
The respective odds ratios for EBUS-positivity in echelon-3 according to the prognostic factors from univariable and multivariable logistic regression analysis were: (i) OR = 12.7 (95%-CI: 3.5–46.4) (p = 0.0001, χ2-test) and OR = 12.1 (95%-CI: 3.2–46.5) (p = 0.0003, χ2-test) in dependence on PET-positivity vs. negativity in echelon-3, (ii) OR = 5.9 (95 CI: 1.3–26.7) (p = 0.021, χ2-test) and OR = 6.7 (95%-CI: 1.31–31.2) (p = 0.022, χ2-test) in dependence on EBUS-positivity vs. negativity in echelon-2, as well as (iii) OR = 2.8 (95%-CI: 1.01–7.9) (p = 0.049, χ2-test) and OR = 4.0 (95%-CI: 1.24–13.2) (p = 0.020, χ2-test) for left-sided tumors compared with right-sided