Fig. 5.

Inhibition of miR-497 in mice reduced CCl₄-induced liver fibrosis. a Collagen deposition shown by Masson staining in the livers from different groups as indicated. b Sirius red staining showed collagen deposition in the livers from different groups as indicated. c Hydroxyproline (HYP) content in the liver of mice in each group as indicated. d Levels of α-SMA, P-Smad2/3, COLI, and COLIII in in the livers from different groups determined by western blot. *P < 0.05, **P < 0.01, compared with the indicated group. All data represent at least three independent experiments