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Overview of the Trycycler long-read assembly pipeline. Before Trycycler is run, the user must generate multiple complete assemblies of the same genome, e.g., by assembling different subsets of the original long-read set. Trycycler then clusters contigs from different assemblies and produces a consensus contig for each cluster. These consensus contigs can then be polished (e.g., with Medaka) and combined into a final high-quality long-read-only assembly
