Table 1.
Clinicopathologic Characteristics of Patients by Receipt of Primary Surgery.
| Characteristic | No. of patients (%) | P-value | Effect size | |
|---|---|---|---|---|
| Non-surgery group (N = 32538) | Surgery group (N = 1074) | |||
| Year of diagnosis | <0.001 | 0.03 | ||
| 2010 | 4892 (15.0) | 199 (18.5) | ||
| 2011 | 4753 (14.6) | 190 (17.7) | ||
| 2012 | 5336 (16.4) | 175 (16.3) | ||
| 2013 | 5710 (17.5) | 163 (15.2) | ||
| 2014 | 5862 (18.0) | 177 (16.5) | ||
| 2015 | 5985 (18.4) | 170 (15.8) | ||
| Sex | 0.577 | - | ||
| Male | 17958 (55.2) | 583 (54.3) | ||
| Female | 14580 (44.8) | 491 (45.7) | ||
| Age, years | <0.001 | 0.06 | ||
| 18-49 | 2115 (6.5) | 113 (10.5) | ||
| 50-54 | 2940 (9.0) | 109 (10.1) | ||
| 55-59 | 4390 (13.5) | 191 (17.8) | ||
| 60-64 | 5200 (16.0) | 187 (17.4) | ||
| 65-69 | 5666 (17.4) | 197 (18.3) | ||
| 70-74 | 4848 (14.9) | 130 (12.1) | ||
| 75-79 | 3754 (11.5) | 107 (10.0) | ||
| 80+ | 3625 (11.1) | 40 (3.7) | ||
| Race | 0.017 | 0.02 | ||
| White | 24975 (76.8) | 864 (80.4) | ||
| Black | 4332 (13.3) | 125 (11.6) | ||
| Othera | 3183 (9.8) | 82 (7.6) | ||
| Unknown | 48 (0.1) | 3 (0.3) | ||
| Marital | <0.001 | 0.02 | ||
| Single | 5217 (16.0) | 172 (16.0) | ||
| Married | 17088 (52.5) | 629 (58.6) | ||
| Otherb | 8935 (27.5) | 231 (21.5) | ||
| Unknown | 1298 (4.0) | 42 (3.9) | ||
| Site | 0.01 | 0.02 | ||
| Lower lobe, lung | 8551 (26.3) | 286 (26.6) | ||
| Lung, NOS | 3140 (9.7) | 71 (6.6) | ||
| Main bronchus | 1531 (4.7) | 50 (4.7) | ||
| Middle lobe, lung | 1352 (4.2) | 49 (4.6) | ||
| Overlapping lesion of lung | 314 (1.0) | 17 (1.6) | ||
| Upper lobe, lung | 17650 (54.2) | 601 (56.0) | ||
| Grade | <0.001 | 0.14 | ||
| Ⅰ | 644 (2.0) | 48 (4.5) | ||
| Ⅱ | 3919 (12.0) | 312 (29.1) | ||
| Ⅲ | 8432 (25.9) | 474 (44.1) | ||
| Ⅳ | 306 (0.9) | 21 (2.0) | ||
| Unknown | 19237 (59.1) | 219 (20.4) | ||
| Histology | <0.001 | 0.03 | ||
| Adenocarcinoma | 23935 (73.6) | 776 (72.3) | ||
| Squamous cell carcinoma | 7112 (21.9) | 212 (19.7) | ||
| Larger cell carcinoma | 907 (2.8) | 48 (4.5) | ||
| Adenosquamous carcinoma | 584 (1.8) | 38 (3.5) | ||
| T stage | <0.001 | 0.04 | ||
| T1 | 4014 (12.3) | 189 (17.6) | ||
| T2 | 9196 (28.3) | 363 (33.8) | ||
| T3 | 8567 (26.3) | 270 (25.1) | ||
| T4 | 10761 (33.1) | 252 (23.5) | ||
| N stage | <0.001 | 0.11 | ||
| N0 | 6776 (20.8) | 467 (43.5) | ||
| N1 | 2615 (8.0) | 146 (13.6) | ||
| N2 | 15250 (46.9) | 349 (32.5) | ||
| N3 | 7897 (24.3) | 112 (10.4) | ||
| Radiation therapy | 0.867 | - | ||
| No | 13595 (41.8) | 452 (42.1) | ||
| Yes | 18943 (58.2) | 622 (57.9) | ||
| Chemotherapy | 0.191 | - | ||
| No | 11738 (36.1) | 366 (34.1) | ||
| Yes | 20800 (63.9) | 708 (65.9) | ||
| Distant metastatic site | ||||
| Distant lymph nodes | <0.001 | 0.03 | ||
| No | 26602 (81.8) | 956 (89.0) | ||
| Yes | 5936 (18.2) | 118 (11.0) | ||
| Bone | <0.001 | 0.08 | ||
| No | 15344 (47.2) | 762 (70.9) | ||
| Yes | 17194 (52.8) | 312 (29.1) | ||
| Brain | <0.001 | 0.03 | ||
| No | 20721 (63.7) | 590 (54.9) | ||
| Yes | 11817 (36.3) | 484 (45.1) | ||
| Liver | <0.001 | 0.05 | ||
| No | 25444 (78.2) | 962 (89.6) | ||
| Yes | 7094 (21.8) | 112 (10.4) | ||
a American Indian/AK Native, Asian/Pacific Islander.
b Widowed/Divorced/Separated/Unmarried or Domestic Partner.