. 2021 Sep 15;16(4):882–891. doi: 10.1007/s11764-021-01081-z

Table 2.

Median (range) scores for secondary outcomes by treatment group (yoga N = 23, control N = 14)

Outcomes	Median (range)^a		Estimate of median change (range, p)		Comparison of change between groups (p)
Outcomes	Yoga	Control	Yoga	Control	Comparison of change between groups (p)
Worst CIPN pain^b
Baseline	5.9 (3.0–9.1)	5.9 (3.6–8.1)^d	− 1.7 (− 7.1 to 0.6, p < 0.0001)*	− 1.6 (− 4.1 to 2.0, p = 0.04)^d*	0.74
Eight weeks	4.0 (0–8.1)	4.2 (1.0–9.0)^d	− 1.7 (− 7.1 to 0.6, p < 0.0001)*	− 1.6 (− 4.1 to 2.0, p = 0.04)^d*	0.74
CIPN sensory^b
Baseline	48.1 (14.8–85.2)	42.6 (22.2–81.5)	− 14.8 (− 40.7 to 11.1, p < 0.0001)*	− 11.1 (− 40.7 to 11.1, p = 0.003)*	0.42
Eight weeks	37.0 (7.4–88.9)	31.5 (7.4–66.7)	− 14.8 (− 40.7 to 11.1, p < 0.0001)*	− 11.1 (− 40.7 to 11.1, p = 0.003)*	0.42
CIPN motor^b
Baseline	33.3 (0–91.7)	25.0 (4.2–66.7)	− 8.3 (− 45.8 to 33.3, p = 0.0004)*	− 8.3 (− 29.2 to 8.3, p = 0.002)*	0.73
Eight weeks	25.0 (0–58.3)	16.7 (0–37.5)	− 8.3 (− 45.8 to 33.3, p = 0.0004)*	− 8.3 (− 29.2 to 8.3, p = 0.002)*	0.73
Pain interference^b
Baseline	59.9 (41.6–75.6)	59.2 (52–66.6)	− 4.6 (− 22.2 to 11.2, p = 0.002)*	− 4.2 (− 18.3 to 5.6, p = 0.03)*	0.99
Eight weeks	53.9 (41.6–69.7)	54.8 (41.6–71.6)	− 4.6 (− 22.2 to 11.2, p = 0.002)*	− 4.2 (− 18.3 to 5.6, p = 0.03)*	0.99
Physical function^c
Baseline	40.5 (33.2–57)	42.7 (30.5–48.3)	3.5 (− 7.6 to 19.1, p = 0.003)*	1.7 (− 11.6 to 11.6, p = 0.22)	0.49
Eight weeks	45.5 (31.9–57)	44.5 (31.9–57)	3.5 (− 7.6 to 19.1, p = 0.003)*	1.7 (− 11.6 to 11.6, p = 0.22)	0.49
Anxiety^b
Baseline	57.7 (40.3–71.2)	53.5 (40.3–71.2)	− 5.6 (− 23.1 to 10.2, p = 0.0007)*	0 (− 19.2 to 15.5, p = 0.65)	0.13
Eight weeks	51.2 (40.3–71.2)	51.2 (40.3–71.2)	− 5.6 (− 23.1 to 10.2, p = 0.0007)*	0 (− 19.2 to 15.5, p = 0.65)	0.13
Depression^b
Baseline	53.9 (41.0–63.9)	45.0 (41.0–53.9)	0 (− 12.9 to 4.9, p = 0.01)*	0 (− 10.8 to 19.5, p = 0.50)	0.04*
Eight weeks	49.0 (41.0–63.9)	49.0 (41.0–60.5)	0 (− 12.9 to 4.9, p = 0.01)*	0 (− 10.8 to 19.5, p = 0.50)	0.04*
Sleep impairment^b
Baseline	59.3 (35.2–66.3)	55.1 (35.2–71.9)	− 5.0 (− 25.1 to 24.6, p = 0.02)*	− 1.2 (− 10.0 to 10.4, p = 0.79)	0.10
Eight weeks	50.3 (30.0–69.5)	54.8 (38.7–69.5)	− 5.0 (− 25.1 to 24.6, p = 0.02)*	− 1.2 (− 10.0 to 10.4, p = 0.79)	0.10
Fatigue^b
Baseline	55.1 (33.7–75.8)	53.1 (43.1–71.6)	− 6.5 (− 14.9 to 21.4, p = 0.002)*	− 1.4 (− 13.6 to 9.6, p = 0.42)	0.05*
Eight weeks	48.6 (33.7–66.7)	53.1 (43.1–71.6)	− 6.5 (− 14.9 to 21.4, p = 0.002)*	− 1.4 (− 13.6 to 9.6, p = 0.42)	0.05*

Note:

^aIncreasing scores for the specified variables indicate worse symptoms, except for physical function, where higher scores represent greater function

^bFor the estimate of median change, negative estimates indicate improvements in symptom severity, whereas positive estimates indicate worsening of symptom severity over time

^cFor the estimate of median change, negative estimates indicate that function worsened over time, whereas positive estimates indicate that function improved over time

^dn = 12

^*Statistically significant (p < 0.05) change from baseline to end of study