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Fragments 161, 426 and 434 within the active site of Mpro. Interactions with the residues inside the cavity are shown as 2D plots. The colored areas correspond to the zone-classification made for the fragments, according to their position within the active site: group 1 (blue area), group 2 (red area) and group 3 (yellow area). (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
