Table 1.
Correlation of Rictor expression with clinicopathological characteristics in 92 gastric cancer patients.
| Factors | Cases | Rictor | |
|---|---|---|---|
| n (%) | P value | ||
| Gender | |||
| Male | 57 | 44(81.5) | 0.238 |
| Female | 35 | 27(77.1) | |
| Age(yr) | |||
| ≤60 | 30 | 22(68.8) | 0.470 |
| >60 | 62 | 49(79.0) | |
| Location | |||
| Upper | 11 | 10(90.9) | 0.173 |
| Central | 24 | 18(75.0) | |
| Lower | 49 | 36(73.5) | |
| Diffuse | 8 | 7(87.5) | |
| Size | |||
| <5cm | 41 | 35(85.4) | 0.019* |
| ≥5cm | 51 | 35(68.3) | |
| Depth of invasion | |||
| TI+T2 | 14 | 13(92.9) | 0.026* |
| T3+T4 | 78 | 58(74.4) | |
| Lymph node metastasis | |||
| Negative | 23 | 18(78.2) | 0.037* |
| Positive | 69 | 53(76.8) | |
| Distant metastasis | |||
| M0 | 84 | 64(76.2) | 0.033* |
| M1 | 8 | 7(87.5) | |
| TNM stage | |||
| I | 9 | 9(100) | 0.009* |
| II | 28 | 20(71.4) | |
| III | 47 | 35(74.5) | |
| IV | 8 | 7(87.5) | |
| Who grading | |||
| Grade 1 | 14 | 14(100) | 0.029* |
| Grade 2 | 68 | 50(73.5) | |
| Grade 3 | 10 | 7(70.0) | |
| Tumor thrombus | |||
| Negative | 79 | 60(75.9) | 0.046* |
| Positive | 13 | 11(84.6) | |
Statistical analysis indicated that Rictor expression was correlated with tumor size, depth of invasion, lymph node metastasis, TNM stage, WHO grading and tumor thrombus. There was no significant association with gender, age, tumor location and distant metastasis. *P < 0.05.