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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Expert Rev Respir Med. 2020 Oct 25;15(3):339–350. doi: 10.1080/17476348.2021.1835475

Table 2.

Presently defined CLAD phenotypes, adapted [3]

Phenotype Obstruction (FEV1/FVC <0.7) Restriction (TLC decline ≥10% from baseline) CT opacities
BOS Yes No No
RAS No Yes Yes
Mixed Yes Yes Yes
Undefined Yes No Yes
Yes Yes No

Abbreviations: BOS, bronchiolitis obliterans syndrome; CLAD, chronic lung allograft dysfunction; CT, computed tomography; FEV1, forced expiratory volume in one second; FVC, forced vital capacity; RAS, restrictive allograft syndrome; TLC, total lung capacity.