Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 14:1–15. doi: 10.1080/07391102.2021.1977698

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Informa UK Limited, trading as Taylor & Francis Group

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

PMC Copyright notice

Figure 4. — Binding modes of shortlisted BSAAs against spike, RdRp, Mpro and helicase. (A) surface representation of structural domains of spike protein with Suramin and Imatinib shown in yellow (B and C) represent 2 D interactions of Suramin and Imatinib with spike, drug molecule is shown in grey ball and stick with interacting residues shown in disc green dotted lines represents hydrogen bonding(D) Surface representation of RdRp structural domains represented in their respective colors (E and F) 2 D representation of molecular interactions of Glycyrrhizin and Imatinib with RdRp catalytic cavity. Green dotted lines represent hydrogen bond while yellow and pink dotted lines represent pi-anion and pi-Sulphur interactions. (G) Surface representation of Mpro domains and features with bound drugs (Verdinexor and Imatinib) in yellow color (H and I) representation of molecular interaction in 2 D form. (J) Surface representation of helicase with domain features in respective colors (K and L) 2 D representation of molecular interaction of Suramin and Glycyrrhizin with ATP binding domain of helicase enzyme.