Figure 2.

Diarrheal infection and antibiotic treatment were common and heterogenous in infants from Mirpur. A, Prevalence of diarrhea. Frequency of diarrheal episodes per child. Full Mirpur cohort is shown in in gray; red subset indicates the children whose samples were used in the microbiome study (and all subsequent figures). B, All-cause diarrhea was heterogenous among children with divergent Cryptosporidium outcomes. Number of diarrheal events per child based on cumulative Cryptosporidium status, both over the first 2 years of life. C, Antibiotic usage was heterogenous among children with divergent Cryptosporidium outcomes. Number of antibiotic events per child based on cumulative Cryptosporidium status, both over the first 2 years of life. Combination therapies were treated as separate doses. For B and C, the full cohort was used and statistics are shown if significant. For B and C, each box represents the median (inner line), 25th percentile, and 75th percentile. Upper whiskers extend from the top of the box to the largest value within 1.5 times the interquartile range (distance between 25th and 75th percentile), and the lower whisker extends to the smallest value within 1.5 times the interquartile range. P values were generated from a t test without multiple testing correction.