Table 3.
Examples of specific matches, general matches, and non-matches between outcomes in systematic reviews and corresponding relevant core outcome sets
| Systematic review ID | Outcome in systematic review | Core outcome set ID | Outcome In core outcome set | Type of match | Comparative assessment of breadth of outcomes |
|---|---|---|---|---|---|
| 59 | HbA1c | 260 | HbA1c | Specific | - |
| 59 | Hypoglycemia | 260 | Hypoglycemic episodes | Specific | - |
| 71 | Weight loss | 247 | Weight | Specific | - |
| 50 | Haemorrhagic stroke | 65 | Stroke | General | Outcome in COS is broader. |
| 36 | Prostate cancer-specific survival | 43 | Survival | General | Outcome in COS is broader. |
| 61 | Asthma exacerbations requiring systemic (oral and/or parenteral) corticosteroids | 60 | Exacerbations | General | Outcome in COS is broader. |
| 57 | Patient-reported outcomes | 29 | Pain | General | Outcome in COS is narrower. |
| 59 | Quality of life | 305 | Diabetes-related quality of life | General | Outcome in COS is narrower. |
| 59 | Hypoglycemic episodes | 305 | Number of severe hypoglycaemic events | General | Outcome in COS is narrower. |
| 38 | Societal costs, including caregiving time/time spent on activities | 95 | Family carer burden | General | Outcome in COS is neither broader nor narrower. |
| 89 | Asthma-related medication adherence | 59 | Frequency of medication | General | Outcome in COS is neither broader nor narrower. |
| 61 | Asthma exacerbations requiring systemic (oral and/or parenteral) corticosteroids | 61 | Exacerbations (within 1-4 weeks) | General | Outcome in COS is neither broader nor narrower. |
| 66 | Depression | 103 | Uric acid | Not a match | - |
| 61 | All-cause mortality | 59 | Symptoms | Not a match | - |
| 38 | Satisfaction with care | 303 | Cognition | Not a match | - |