Fig. 7. Serological response in unvaccinated and FIV-vaccinated macaques.

IgG was quantified by ELISA to recombinant NP, RBD, and full-length trimeric and stabilized spike protein (Spike). Bars are geometric mean titers. The significance of any difference from pre- to postvaccination is shown, determined by a paired t test. The microneutralization 50% titer (ND₅₀) is also shown with samples obtained pre- and postvaccination and following SARS-CoV-2 challenge. Bars are geometric mean ND₅₀ titers.