Table 02.

Association of SERT (s) Carrier Status with Comorbidities, Whole Sample (N=628)

Index Condition	Alcohol Dependence	Alcohol Abuse	Major Depressive DO	Bipolar Disorder	Psychotic Disorders	Panic Disorder	Agoraphobia	Social Phobia	Obsessive Comp DO	Gen Anxiety DO	Anxiety DO NOS	Dysthymic Disorder	Depr DO NOS	Simple Phobia	Adjust DO Dep Mood	Opioid Dependence
Alcohol Dependence	N/A	1.5	0.6	3.1			1.6	1.2		0.2	0.7		0.2	0.5	2.3	1.3
Alcohol Abuse	1.6	N/A	0.4			3.4		1.6						0.2		0.7
Major Depressive Disorder	0.7	0.5	N/A			2.0	2.3	5.1*	0.3	0.7	0.4	1.7		1.0		1.4
Bipolar Disorder	1.7			N/A			0.1	0.2
Psychotic Disorders					N/A			1.0
Panic Disorder		1.3	0.4			N/A	0.7	3.1	0.3						0.3	0.6
Agoraphobia	3.5		4.7*	0.5		3.3	N/A	1.1						0.6		1.1
Social Phobia	1.0	1.4	4.8*	0.6	0.7	6.2	0.6	N/A	0.2	1.4			0.7	0.7	1.3	2.1
Obsessive Compulsive DO			1.0			5.0		0.5	N/A
Generalized Anxiety Disorder	0.2		1.0					4.0		N/A				1.4
Anxiety Disorder NOS	0.8		0.3								N/A			2.0
Dysthymic Disorder			3.0									N/A		1.0
Depressive Disorder NOS	0.2							1.0					N/A			2.4
Simple Phobia Disorder	0.7	0.2	1.3				0.7	1.3		1.0	2.1	1.0		N/A	1.0	2.1
Adjust DO Depressed Mood	2.7					0.8		1.7						0.7	N/A
Opioid Dependence	1.5	0.8	1.5			1.7	0.8	2.7					1.7	1.7		N/A

Table 02 summarizes the ratio of the odds of the SERT (S) allele carriers to the odds of the non-carriers, of the comorbidity for the conditions listed in the column headings (Condition B), on those subjects who have been diagnosed with the index condition listed in the row headings (Condition A or Index). Blank cells represent associations with insufficient numbers to complete calculation.

^*Marks Ratios that achieved statistical significance (p<0.05)